ABSTRACT
To determine the influence of a modified compression shell [with a cut out free space for the cornea] in guarded filtration procedures on flat anterior chambers, final intraocular pressure [IOP] reduction, success rate, tenon capsule cyst [TCC] and bleb appearance in patients with primary open angle glaucoma, we randomized in a prospective clinical trial 33 patients divided into two groups: Group A, 15 patients in whom the shell was applied immediately postoperatively; and group B, 18 patients without shell. Both groups were similar in age, sex, diagnosis and preoperative IOP. The shell was applied at the end of each surgery and used for three days postoperatively. There was no statistical difference after surgery in the incidence of flat anterior chamber [2/15 in group A and 3/18 in group B]. Also, there was no difference after three months in term of bleb appearance, but there was a tendency of fewer TCC in those receiving the shell [1/15 in group A and 3/18 in group B]. After two years there was no statistical difference in IOP reduction or in success rate in either group [73.5 percent group A and 72.5 percent group B]. Success is defined as 5 mmHg <22, with reduction of medication and no carbonic anhydratse inhibitors
Subject(s)
Sclera/physiopathology , Eye DiseasesABSTRACT
The effect of Mydriacil [Tropicamide] 1 percent and phenylephrine [Neo-synephrine] 10 percent eye drops used frequently as mydriatics in daily ophthalmic practice on the intra-ocular pressure [IOP] of 30 normal subjects [60 years], was studied. Each drug was applied to one eye of the same individual. There was a minimal rise in IOP from the pretreatment level in 43.33 percent of cases [13/30] after application of Mydriacil ranging between 1-5 mmHg. after 30 minutes, and a drop in IOP in 10 percent [3/30] between 1-3 mmHg. With phenylephrine the rise occurred in 36.67 percent [11/30] and ranged between 1-6 mmHg. The drop of IOP occurred in 20 percent [6/30] of eyes between 1-3 mmHg. Although the change in IOP in all cases was statistically insignificant, it is preferable to examine the angle, especially in dark pigmented irides prior to dilating the pupil with either drug
Subject(s)
Humans , Phenylephrine , Comparative StudyABSTRACT
Many drugs are used in the management of glaucoma, each exerting its effect through a certain mechanism. The interaction of two or more of these drugs administered concomittently is of importance to the ophthalmologist. Such interaction may reduce the intraocular pressure [IOP], or may antagonize the intended therapeutic effect of any of them. The effect of pilocarpine, timolol, eserine and diamox, each alone and in different combinations was studied clinically in 149 eyes of chronic simple glaucoma, and experimentally in albino rabbits. The results showed that pilocarpine remains the most effective and safest topical drug for prolonged use in open angle glaucoma. The use of timolol is accompanied by two phenomena "the short term escape" and the "long term drift". Combining it with another drug after one year of its use is essential to keep its efficiency. Pilocarpine-acetazolamide is the most effective combination in reducing IOP compared to all other combinations
Subject(s)
Humans , Male , Female , Glaucoma/drug therapy , Trabeculectomy , Drug Interactions , Follow-Up StudiesABSTRACT
An organised survey of the inhabitants off Hurghada attending the outpatient clinic and of school children was carried out. Among the 300 outpatient clinic visitors, pterygium was searched for in adults and refractive errors in children below 15 years of age. Pterygium was found ion 5% of patients [15/300]. Of the 720 school children examined, a search for the different stages of trachoma and refractive errors was stressed upon. Two hundred and ninety two [292] children [40.56%] were affected with different stages off trachoma, while 112 [15.6%] had refractive errors. One hundred and thirty [130] persons were randomly selected to test for the incidence of toxoplasmosis, of them 15 persons [11.54%] gave positive results